Hyperthermic Intraperitoneal Chemotherapy
Information
- Drug Name
- Hyperthermic Intraperitoneal Chemotherapy
- Description
- Entry(CIViC)
- 1
CIViC
| Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| peritoneal mesothelioma | EGFR MUTATION EGFR MUTATION | B |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 4 | 20942962 | Detail |
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| 25 patients with metastatic peritoneal mesotheliom... | EGFR | EGFR MUTATION EGFR MUTATION | Sensitivity | true | CIViC Evidence | detail |
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02124421 | Active, not recruiting | Phase 2 | HOT: HIPEC in Ovarian Cancer as Initial Treatment | April 2014 | April 2028 |
| NCT01580410 | Completed | Phase 2 | Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix | May 2009 | November 2016 |
| NCT02891447 | Completed | Phase 2 | Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal Cancer | September 1, 2016 | April 11, 2023 |
| NCT01091636 | Completed | Phase 2/Phase 3 | Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Ovarian Cancer | March 2010 | January 10, 2020 |
| NCT05753306 | Recruiting | Phase 2 | Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study | March 16, 2023 | February 1, 2026 |
| NCT02754115 | Recruiting | An Audit of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy | April 2016 | January 2027 | |
| NCT04213794 | Recruiting | Early Phase 1 | Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients | November 8, 2019 | January 30, 2025 |
| NCT04858009 | Recruiting | Phase 2 | Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis | January 5, 2024 | May 2026 |
| NCT05001880 | Recruiting | Phase 2 | Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma | March 22, 2022 | August 20, 2025 |
| NCT05415709 | Recruiting | Early Phase 1 | Hyperthermic Intraperitoneal Chemotherapy With Cisplatin During Surgery or Cisplatin Before Surgery for the Treatment of Stage III or IV Ovarian, Fallopian Tube or Peritoneal Cancer | June 13, 2022 | December 31, 2024 |
| NCT03373058 | Unknown status | Phase 3 | Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery | October 15, 2019 | July 1, 2023 |
| NCT03604614 | Unknown status | Phase 2 | Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer With Peritoneal Metastatis | June 1, 2017 | August 24, 2020 |
| NCT02356276 | Unknown status | Phase 3 | Efficacy of HIPEC in the Treatment of Locally Advanced Gastric Cancer After radIcal Gastrectomy With D2 | May 11, 2015 | January 2022 |
| NCT04280185 | Unknown status | N/A | HIPEC in the Treatment of Stage IIc-IV Epithelial Ovarian Cancer After CRS (HIPECOC) | June 1, 2020 | May 1, 2024 |
| NCT03180177 | Unknown status | Phase 3 | Efficacy of HIPEC as NACT and Postoperative Chemotherapy in the Treatment of Advanced-Stage Epithelial Ovarian Cancer | March 1, 2018 | July 1, 2022 |
| NCT02969122 | Unknown status | N/A | Treatment Strategy for Stage IV Gastric Cancer With Positive Peritoneal Cytology as the Only Non-curable Factor | November 2016 | December 2023 |
| NCT03023436 | Unknown status | Phase 3 | Cytoreductive Surgery Combined With HIPEC and Chemotherapy for Gastric Cancer With Peritoneal Metastasis | January 2016 | June 2022 |
| NCT02850874 | Withdrawn | Phase 2 | HIPEC as Neoadjuvant Treatment for Resectable Pancreatic Adenocarcinoma | February 2016 | December 2016 |